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PFAS Exposure Linked to Weight Regain After Teen Bariatric Surgery
USC researchers found that adolescents with higher pre-surgery blood levels of PFAS regained more weight after bariatric surgery than those with lower levels. The study links PFAS exposure to reduced long-term treatment success.
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How AI Could Speed the Development of RNA Vaccines and Therapies
Using artificial intelligence, researchers have come up with a new way to design nanoparticles that can more efficiently deliver RNA vaccines and other types of RNA therapies.
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Researchers Remodel Failed Malaria Drug Into a Winner
A new generation of malaria drugs failed clinical trials, in part because they were hard to swallow. UCSF chemists remodeled their structures to make them more soluble, while maintaining their effectiveness against drug-resistant parasites.
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Custom Nanoparticle Unlocks the Anti-Inflammatory Potential of Citrus
Scientists have developed a bio-engineered molecule that uses a natural compound found in citrus fruits to target and treat inflammation.
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New Antibacterials Found in Archaea
How archaea compete with and defend themselves against bacteria has revealed new antibacterials that kill bacteria by targeting the peptidoglycan cell wall.
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Engineered Antibody Eliminates Aggressive Cancers in Clinical Trials
In a Phase 1 clinical trial of an immunotherapy drug, dubbed 2141-V11, of the 12 patients included, 6 patients saw their tumors shrink, including 2 who saw them disappear completely.
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Prenatal Painkiller Use Associated With Autism, ADHD in Children
Mount Sinai researchers used the Navigation Guide methodology to review 46 studies on prenatal acetaminophen exposure. Higher-quality studies showed a stronger link to autism spectrum disorder and ADHD.
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AI-Designed Antibiotics Show Promise Against Drug-Resistant Bacteria
Researchers at MIT have developed novel antibiotics using generative AI, targeting two drug-resistant bacterial pathogens: Neisseria gonorrhoeae and methicillin-resistant Staphylococcus aureus (MRSA).
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Experimental mRNA-Based Therapy Shows Promise as a Universal Antiviral
Taking inspiration from a rare mutation that makes people impervious to viral diseases, a Columbia researcher is developing a therapy that could bestow this superpower on the rest of us.
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Drug for Spinal Muscular Atrophy Safe and Effective in Newborns
Results from an international clinical trial found that risdiplam, a drug used to treat the rare neurodegenerative disorder Spinal Muscular Atrophy, is safe and effective in newborns.
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