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AI Discovers New Antibiotics in Ancient Microbes
Researchers have used AI to identify previously unknown compounds in some of Earth's oldest microbial lifeforms that could have applications in developing next-generation antibiotics.
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Sugar-Coated Particle Reduces COVID-19 Infection Rate by Nearly 99%
Research led by a Swansea University academic has revealed a synthetic glycosystem — a sugar-coated polymer nanoparticle — that can block COVID-19 from infecting human cells, reducing infection rates by nearly 99%.
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AI Automatically Designs Optimal Drug Candidates for Cancer-Targeting Mutations
A new AI model can design and optimize drug candidate molecules tailored to a protein’s structure alone – without needing prior information about binding molecules.
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Antifungal Drug Candidates Discovered in University Greenhouse
A research team at McMaster University has discovered a new drug class that could someday lead to treatments for dangerous fungal infections. The new molecules, dubbed coniotins, were isolated from a plant-dwelling fungus.
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How a Parasitic Worm Suppresses Neurons in the Skin
New research has pinpointed how a parasitic worm that causes schistosomiasis suppresses neurons in the skin to evade detection.
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Repurposed Drug Makes RNA Therapies for Inflammatory Diseases Safer
Two new solutions can help alleviate inflammation associated with the use of lipid nanoparticles in RNA therapies, while still getting RNA where it needs to be in the cell.
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Rejuvenating Nuclear Speckles Offers New Approach to Treating Neurodegeneration
Targeting cellular structures called nuclear speckles could be a completely new approach for treating proteinopathies, including Alzheimer's, Parkinson's and prion diseases.
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High-Potency Synthetic Opioids Are Changing How Doctors Treat Opioid Use Disorder
Researchers surveyed 58 directors of hospital-based addiction consult services (ACS) and found that most ACS recognized the prevalence of high-potency synthetic opioids and agreed they have changed how they approach medication initiation.
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Dormant Tumor Cells Found To Fuel Neuroblastoma Relapse
Researchers found that MYCN located on extra-chromosomal DNA enables some neuroblastoma cells to enter a dormant, therapy-resistant state. Combining chemotherapy with drugs targeting senescent cells removed aggressive and dormant cells in models.
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Why High-Performance Athletes Aren’t Immune to Depression
A new book reveals that elite athletes face distinct depression risks despite exercise’s protective effects. Pressures such as performance demands, injury fears and career transitions can undermine mental health.
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