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A scientist in a white coat holding up a digitally-imposed image of a red and white drug pill, glowing faintly with data-like lines.
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AI Discovers New Antibiotics in Ancient Microbes

Researchers have used AI to identify previously unknown compounds in some of Earth's oldest microbial lifeforms that could have applications in developing next-generation antibiotics.
SARS-CoV-2 the virus responsible for COVID-19.
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Sugar-Coated Particle Reduces COVID-19 Infection Rate by Nearly 99%

Research led by a Swansea University academic has revealed a synthetic glycosystem — a sugar-coated polymer nanoparticle — that can block COVID-19 from infecting human cells, reducing infection rates by nearly 99%.
Columns of blue and pink light, emitted from a board of data-like signals.
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AI Automatically Designs Optimal Drug Candidates for Cancer-Targeting Mutations

A new AI model can design and optimize drug candidate molecules tailored to a protein’s structure alone – without needing prior information about binding molecules.
A female scientist in PPE holding up a red pill, representing drug discovery.
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Antifungal Drug Candidates Discovered in University Greenhouse

A research team at McMaster University has discovered a new drug class that could someday lead to treatments for dangerous fungal infections. The new molecules, dubbed coniotins, were isolated from a plant-dwelling fungus.
A neuron, representing cells that are suppressed by parasitic worms for them to evade detection.
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How a Parasitic Worm Suppresses Neurons in the Skin

New research has pinpointed how a parasitic worm that causes schistosomiasis suppresses neurons in the skin to evade detection.
A lipid nanoparticle containing RNA approaching a cell.
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Repurposed Drug Makes RNA Therapies for Inflammatory Diseases Safer

Two new solutions can help alleviate inflammation associated with the use of lipid nanoparticles in RNA therapies, while still getting RNA where it needs to be in the cell.
Nuclear speckles merge with chromatin in a colorized microscopy image, illustrating a potential target for neurodegenerative diseases.
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Rejuvenating Nuclear Speckles Offers New Approach to Treating Neurodegeneration

Targeting cellular structures called nuclear speckles could be a completely new approach for treating proteinopathies, including Alzheimer's, Parkinson's and prion diseases.
Various types of drugs including opioids on a desk.
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High-Potency Synthetic Opioids Are Changing How Doctors Treat Opioid Use Disorder

Researchers surveyed 58 directors of hospital-based addiction consult services (ACS) and found that most ACS recognized the prevalence of high-potency synthetic opioids and agreed they have changed how they approach medication initiation.
Fluorescent microscopy image of neuroblastoma cells showing bright blue, pink, and green markers against a black background.
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Dormant Tumor Cells Found To Fuel Neuroblastoma Relapse

Researchers found that MYCN located on extra-chromosomal DNA enables some neuroblastoma cells to enter a dormant, therapy-resistant state. Combining chemotherapy with drugs targeting senescent cells removed aggressive and dormant cells in models.
Focused male athlete in a blue tank top riding a stationary bike in a gym.
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Why High-Performance Athletes Aren’t Immune to Depression

A new book reveals that elite athletes face distinct depression risks despite exercise’s protective effects. Pressures such as performance demands, injury fears and career transitions can undermine mental health.
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