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A Closer Look at the Immune Response to Influenza
Understanding how porcine immune systems respond to influenza infection could improve therapies and vaccines for pigs and humans.
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Prenatal Painkiller Use Associated With Autism, ADHD in Children
Mount Sinai researchers used the Navigation Guide methodology to review 46 studies on prenatal acetaminophen exposure. Higher-quality studies showed a stronger link to autism spectrum disorder and ADHD.
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Evolutionary DNA Change May Boost Human Thinking Skills
Scientists identified HAR123, a human-accelerated genomic region acting as a transcriptional enhancer that regulates brain cell development. HAR123 influences the balance of neurons and glial cells, potentially enhancing cognitive flexibility.
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Experimental mRNA-Based Therapy Shows Promise as a Universal Antiviral
Taking inspiration from a rare mutation that makes people impervious to viral diseases, a Columbia researcher is developing a therapy that could bestow this superpower on the rest of us.
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Ancient DNA Reveals West African Ancestry in Early Medieval England
Ancient DNA from two individuals buried in 7th-century cemeteries in Kent and Dorset reveals each had a West African grandparent. Despite their diverse heritage, both were buried as local community members.
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Drug for Spinal Muscular Atrophy Safe and Effective in Newborns
Results from an international clinical trial found that risdiplam, a drug used to treat the rare neurodegenerative disorder Spinal Muscular Atrophy, is safe and effective in newborns.
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Genetic Biomarker Predicts Optimal Treatment for Multiple Sclerosis
Researchers have identified a genetic biomarker that predicts whether multiple sclerosis (MS) patients will respond particularly well to treatment with glatiramer acetate. The results come from a multicentre analysis of more than 3,000 MS patients.
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Male Researchers Retract More Papers Than Their Female Peers
A new global study reveals that male researchers have higher paper retraction rates than their female peers. We spoke to the lead author to find out why this could be the case.
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Scientists Combine AI and CRISPR for Safer, More Accurate DNA Edits
University of Zurich researchers have developed Pythia, an AI tool that predicts how cells repair DNA after CRISPR cuts, guiding ultra-precise edits. Tested in human cells, frogs, and mice, the method improves safety and accuracy.
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Exercise May Slow or Reverse Epigenetic Aging
A research perspective links structured exercise and high fitness levels to slower epigenetic aging, measured via DNA methylation changes. Evidence from human and animal studies suggests aerobic and strength training can reduce biological age markers
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